Efficacy assessment of the clinical dermoscopy and vulvoscopy examination in vulvar intraepithelial neoplasia





squamous intraepithelial lesions of the vulva, dermoscopy, vulvoscopy, human papillomavirus


High grade squamous intraepithelial lesions of the vulva of the usual type are associated with infection caused by human papillomavirus, while differentiated intraepithelial neoplasia of the vulva develops most often on the background of vulvar lichen sclerosus et atrophicus in postmenopausal women. These types of intraepithelial neoplasia can be analyzed using dermoscopy and vulvoscopy methods.

Purpose - to evaluate the effectiveness of clinical dermatoscopy and vulvoscopic examination in vulvar intraepithelial neoplasia.

Materials and methods. This research paper presents the results of using dermoscopy and vulvoscopy examination methods, their comparison with the histological result and determining the most effective of these methods taking into account a higher probability of suspected precancerous lesions of the vulva.

Results. The study involved 170 patients who were examined in the outpatient department of the National Cancer Institute in 2017-2021. 100 (58.82%) patients were diagnosed with the usual type vulvar intraepithelial neoplasia, 70 (41.17%) patients - of the differentiated type.

Conclusions. The study results proved that dermoscopy was more exact to suspect precancer and a more accurate biopsy taking was fixed. The detection of НSIL was 98% in patients who underwent dermoscopy and those who had vulvoscopy - 75%, compared with histological findings.

The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of all participating institutions. The informed consent of the patient was obtained for conducting the studies.

No conflict of interests was declared by the authors.


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