The effectiveness of the elimination diet in improving quality of life indicators in the childbearing age women with symptomatic adenomyosis




symptomatic endometriosis, dienogest, elimination diet, quality of life


The prevalence and growth in the number of cases of symptomatic adenomyosis is largely correlated with the rate of growth in the level of metabolic pathology in the population, in particular, disorders of carbohydrate metabolism.

Purpose - to investigate the impact of the results of the elimination diet on the indicators of the quality of life of women with symptomatic adenomyosis.

Materials and methods. A study and comparison of quality of life indicators (SF-36 questionnaire) was conducted in 120 women with symptomatic adenomyosis, which were divided into 4 groups: the Group I (n=30) was prescribed dienogest treatment, in the other three groups there were 30 women each, who were recommended to exclude from the diet products of deep industrial processing and dairy products (the Group II) or gluten-containing products (the Group III) or both dairy and gluten-containing products (the Group IV). The comparison group consisted of 30 healthy women (without adenomyosis). Statistical data processing was carried out using the SPSS 21 program.

Results. Comparison of quality of life indicators of women without adenomyosis and patients with adenomyosis has shown significant differences in the average values of all components comprising the concept of “quality of life” according to the SF-36 protocol (p<0.05). Compared with women of the Group I, patients of the Groups II and IV had significantly higher total components of physical (PCS) and mental (MCS) health (p<0.05), and women of the Group III had a significantly higher PCS index (p=0.005), but not MCS.

Conclusions. An elimination diet considering the identified type of food intolerance improves quality of life of childbearing age women with symptomatic adenomyosis.

The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies.

No conflict of interests was declared by the authors.

Author Biographies

M.S. Lonshakova, Shupyk National Healthcare University of Ukraine, Kyiv

Kyiv City Center of Reproductive and Perinatal Medicine, Ukraine

L.V. Suslikova, Shupyk National Healthcare University of Ukraine, Kyiv

Clinic of reproductive technologies Ukrainian State Institute of Reproductive Medicine of the Shupyk National Medical University of Healthcare of Ukraine, Kyiv

A.V. Serbenyuk, Shupyk National Healthcare University of Ukraine, Kyiv

Kyiv City Center of Reproductive and Perinatal Medicine, Ukraine


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