Modern view on the problem of uterine leiomyoma in during pregnancy

Authors

DOI:

https://doi.org/10.15574/HW.2024.6(175).6368

Keywords:

uterine leiomyoma, pregnancy, preterm birth, estrogens, treatment, obstetric complications

Abstract

Aim - analyze the data from current literature from etiopathogenetic officials, diagnosis and treatment of uterine leiomyoma before pregnancy and during the hour of pregnancy with the drive, improving the tactics of managing the postnatal and post-natal period in women with uterine leiomyoma, changing the complexity of bandages with bleeding.

The relevance of the problem of uterine leiomyoma throughout the world is described. Looked at etiopathogenetic officials who are responsible for the disease. The emphasis is placed on the complications and causes of uterine leiomyoma in vaginal patients. Analyzed the effectiveness of methods for diagnosing and treating uterine leiomyomas in women. Examination of the influx of uterine leiomyomas on the treatment of vagusity, uterine ruptures, erectile dysfunction, placental folds, postpartum bleeding and other obstetric problems.

Conclusions. Regardless of the current diagnosis and pharmacological factors, the problem of managing vaginity, pregnancy and the postnatal period in women with uterine leiomyoma is lost, the fragments of hormonal imbalance and the plumpness itself accumulates. disruption of the sensory function of the myometrium, leading to recurrent bleeding. The results highlight the need to optimize tactics for managing the third postnatal period and early postnatal period in women with uterine leiomyoma.

The authors declare no conflict of interest.

References

Arisoy R, Erdogdu E, Bostancι E et al. (2016). Obstetric outcomes of intramural leiomyomas in pregnancy. Clin Exp Obstet Gynecol. 43(6): 844-848. https://doi.org/10.12891/ceog3058.2016

Blitz MJ, Rochelson B, Augustine S, Greenberg M, Sison CP, Vohra N. (2016). Uterine fibroids at routine second-trimester ultrasound survey and risk of sonographic short cervix. J Matern Fetal Neonatal Med. 29(21): 3454-3460. https://doi.org/10.3109/14767058.2015.1131261; PMid:26653679

Cagan M, Tanacan A, Donmez HG, Fadiloglu E, Unal C, Beksac MS. (2020). The effect of small size uterine fibroids on pregnancy outcomes in hgh-risk pregnancies. Rev Bras Ginecol Obstet. 42: 535-539. https://doi.org/10.1055/s-0040-1713913; PMid:32992356 PMCid:PMC10309216

Carranza-Mamane B, Havelock J, Hemmings R. (2015). Reproductive Endocrinology and Infertility Committee. The management of uterine fibroids in women with otherwise unexplained infertility. J Obstet Gynaecol Can. 37: 277-285. https://doi.org/10.1016/S1701-2163(15)30318-2; PMid:26001875

Choudhary A, Inamdar SA, Sharma U. (2023). Pregnancy With Uterine Fibroids: Obstetric Outcome at a Tertiary Care Hospital of Central India. Cureus. 15(2): e35513. https://doi.org/10.7759/cureus.35513

Cianci S, Gulino FA, Palmara V et al. (2023). Exploring Surgical Strategies for Uterine Fibroid Treatment: A Comprehensive Review of Literature on Open and Minimally Invasive Approaches. Medicina (Kaunas). 60(1): 64. https://doi.org/10.3390/medicina60010064; PMid:38256325 PMCid:PMC10820219

Ciavattini A, Clemente N, Delli Carpini G, Di Giuseppe J, Giannubilo SR, Tranquilli AL. (2015). Number and size of uterine fibroids and obstetric outcomes. J Matern Fetal Neonatal Med. 28(4): 484-488. https://doi.org/10.3109/14767058.2014.921675; PMid:24803127

Coronado GD, Marshall LM, Schwartz SM. (2000). Complications in pregnancy, labor, and delivery with uterine leiomyomas: a population-based study. Obstet Gynecol. 95(5): 764-769. https://doi.org/10.1016/S0029-7844(99)00605-5; PMid:10775744

Datir SG, Bhake A. (2022). Management of Uterine Fibroids and Its Complications During Pregnancy: A Review of Literature. Cureus. 14(11): e31080. https://doi.org/10.7759/cureus.31080; PMid:36475121 PMCid:PMC9719606

Dumitrașcu MC, Nenciu CG, Nenciu AE, Călinoiu A, Neacșu A et al. (2023, Mar 20). Laparoscopic myomectomy - The importance of surgical techniques. Front Med (Lausanne). 10: 1158264. doi: 10.3389/fmed.2023.1158264. Erratum in: Front Med (Lausanne). 2023 Aug 21; 10: 1251421. https://doi.org/10.3389/fmed.2023.1251421; PMid:37671404 PMCid:PMC10475987

Giuliani E, As-Sanie S, Marsh EE. (2020). Epidemiology and management of uterine fibroids. Int J Gynaecol Obstet. 149(1): 3-9. https://doi.org/10.1002/ijgo.13102; PMid:31960950

Harlev A, Wainstock T, Walfisch A, Landau D, Sheiner E. (2019). Perinatal outcome and longterm pediatric morbidity of pregnancies with a fibroid uterus. Early Human Development. 129: 33-37. https://doi.org/10.1016/j.earlhumdev.2019.01.004; PMid:30639463

Jayes FL, Liu B, Feng L, Aviles-Espinoza N, Leikin S, Leppert PC. (2019). Evidence of biomechanical and collagen heterogeneity in uterine fibroids. Plos One. 14(4): e0215646. https://doi.org/10.1371/journal.pone.0215646; PMid:31034494 PMCid:PMC6488189

Kaminskiy VV, Prokopovych EV. (2018). Clinical experience of using GnRH agonists in the treatment of uterine leiomyoma with concomitant gynecological pathology. Health of woman. 10(136):22-25. https://doi.org/10.15574/HW.2018.136.22

Karlsen K, Schiøler Kesmodel U, Mogensen O, Humaidan P, Ravn P. (2020). Relationship between a uterine fibroid diagnosis and the risk of adverse obstetrical outcomes: a cohort study. BMJ Open. 10(2): e032104. https://doi.org/10.1136/bmjopen-2019-032104; PMid:32071172 PMCid:PMC7044982

Kuziomens'ka M, Chyrva S. (2021). Perebih vahitnosti i rozrodzhennia u zhinok z rubtsem na mattsi pislia miomektomii iz zastosuvanniam endoskopichnykh tekhnolohii. Reproduktyvne zdorovia zhinky. (4): 76-82. https://doi.org/10.30841/2708-8731.4.2021.238166

Landman AJEMC, Don EE, Vissers G, Ket HCJ, Oudjik MA, de Groot CJM et al. (2022). The risk of preterm birth in women with uterine fibroids: A systematic review and meta-analysis. PLoS ONE. 17: e0269478. https://doi.org/10.1371/journal.pone.0269478; PMid:35653408 PMCid:PMC9162311

Litvak OO. (2019). Influence of medicamental correction on morphological changes of leiomyoma of uterus. Health of woman. 1(137): 101-104. https://doi.org/10.15574/HW.2019.137.101

Mitro SD, Sundaram R, Chen Z et al. (2023). Leiomyomata, neonatal anthropometry, and pregnancy outcomes in singleton pregnancies. Ann Epidemiol. 80: 43-52. https://doi.org/10.1016/j.annepidem.2023.02.008; PMid:36822279 PMCid:PMC10040437

Pérez-Roncero GR, López-Baena MT, Ornat L, Cuerva MJ, Garcia-Casarrubios P, Chedraui P et al. (2020). Uterine fibroid and preterm birth risk: a systematic review and meta-analysis. Journal of Obestrics and Gynecology Research. 46: 1711-1727. https://doi.org/10.1111/jog.14343; PMid:32633025

Poulsen BB, Munk T, Rudnicki M, Ravn P. (2017). Ugeskr Laeger. [Uterine fibroids]. 179(43): V04170287.

Saleem HA, Albalwi N, Ba'Abbad L. (2023). Uterine rupture in a term pregnancy after a previous uterine artery embolization to manage a large fibroid. A case report. Case Rep Womens Health. 39: e00551. https://doi.org/10.1016/j.crwh.2023.e00551; PMid:37829161 PMCid:PMC10565681

Saleh HS, Mowafy HE, Hameid AAAE, Sherif HE, Mahfouz EM. (2018). Does Uterine Fibroid Adversely Affect Obstetric Outcome of Pregnancy Biomed Res Int. 2018: 8367068. https://doi.org/10.1155/2018/8367068; PMid:30151390 PMCid:PMC6087613

Semeniak AV, Yuz'ko OM, Nitsovych IR. (2018). Leiomioma matky ta vahitnist'. Neonatolohiia, khirurhiia ta perynatal'na medytsyna. 2(28): 93-98.

Sobel M, Hobson S, Chan C. (2022). Uterine fibroids in pregnancy. CMAJ. 194(22): E775. https://doi.org/10.1503/cmaj.211530; PMid:35667671 PMCid:PMC9177202

Tinelli A, Favilli A, Lasmar RB et al. (2019). The importance of pseudocapsule preservation during hysteroscopic myomectomy. Eur J Obstet Gynecol Reprod Biol. 243: 179-184. https://doi.org/10.1016/j.ejogrb.2019.09.008; PMid:31585677

Tîrnovanu MC, Lozneanu L, Tîrnovanu ŞD et al. (2022). Uterine Fibroids and Pregnancy: A Review of the Challenges from a Romanian Tertiary Level Institution. Healthcare (Basel). 10(5): 855. https://doi.org/10.3390/healthcare10050855; PMid:35627994 PMCid:PMC9141014

Tykha VG, Skripchenko NY. (2019). An algorithm for assisting women with leiomyoma in the postpartum period. Perinatologiya i pediatriya. 1(77): 25-29. https://doi.org/10.15574/PP.2019.77.25

Van Heertum K, Barmat L. (2014). Uterine fibroids associated with infertility. Womens Health (Lond). 10(6): 645-653. https://doi.org/10.2217/WHE.14.27; PMid:25482490

Vilos GA, Allaire C, Laberge PY, Leyland N; SPECIAL CONTRIBUTORS. (2015). The management of uterine leiomyomas. J Obstet Gynaecol Can. 37(2): 157-178. https://doi.org/10.1016/S1701-2163(15)30338-8; PMid:25767949

Yang Q, Ciebiera M, Bariani MV et al. (2022). Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment. Endocr Rev. 43(4): 678-719. https://doi.org/10.1210/endrev/bnab039; PMid:34741454 PMCid:PMC9277653

Yan L, Yu Q, Zhang YN et al. (2018). Effect of type 3 intramural fibroids on in vitro fertilization-intracytoplasmic sperm injection outcomes: a retrospective cohort study. Fertil Steril. 109(5): 817-822.e2. https://doi.org/10.1016/j.fertnstert.2018.01.007; PMid:29605409

Yerezhepbayeva M, Terzic M, Aimagambetova G, Crape B. (2022). Comparison of two invasive non-surgical treatment options for uterine myomas: uterine artery embolization and magnetic resonance guided high intensity focused ultrasound-systematic review. BMC Womens Health. 22(1): 55. https://doi.org/10.1186/s12905-022-01627-y; PMid:35241063 PMCid:PMC8896369

Zhylka NYa. (2017). Doing patients with leyomyoma uterus. Conservative treatment methods (Overview of the Canadian SOGC Clinical Manual). Health of woman. 5(121): 86-91

Published

2024-12-15