Treatment of an acne patient with comorbid chronic chlamydial urethrocervicitis and immune deficiency

Authors

DOI:

https://doi.org/10.15574/HW.2025.2(177).97100

Keywords:

acne, immune deficiency (immunodeficiency), comorbidity, patient-centered care, Chlamydia trachomatis

Abstract

Aim - demonastration of the possibility of using a patient-centered approach to medical care in clinical practice in the treatment of comorbid acne, chronic chlamydial urethrocervicitis and immunodeficiency of the first degree.

Clinical case. A patient-centered approach was used in the supervision of patient H., 25 years old, who turned to a multidisciplinary medical institution for specialized dermatovenereological care. The diagnosis was established: acne, papulo-pustular form, moderate severity, immune deficiency of the first degree, chronic chlamydial urethrocervicitis in the acute stage. Acne treatment was carried out with the help of isotretinoin and a set of cosmetic measures. Elimination of Chlamydia trachomatis was carried out by the consistent use of antibacterial drugs linezolid and levofloxacin, and immunomodulation was carried out with the preparation of antimicrobial regulatory peptides derived from bovine embryonic tissue.

Chlamydia trachomatis was completely eliminated from the genitourinary system, and immunogram indicators were almost completely restored to the level of reference values. At the end of the 6th month of treatment with isotretinoin as part of complex therapy, inflammatory rashes on the patient's face completely stopped, post-acne phenomena decreased significantly. 

Conclusions. In a clinical case, the use of a patient-centered approach to medical care in  the treatment of comorbid acne, chronic chlamydial urethrocervicitis and immunodeficiency of the first degree was demonstrated. The success of treatment was due to well-chosen antibiotic therapy, the use of a complex of cosmetic measures, the use of isotretinoin in a dose appropriate to the clinical picture of acne and the use of Propes as an immunomodulatory means.

The study was conducted in accordance with the principles of the Declaration of Helsinki. Informed consent was obtained from participant.

The author declares no conflict of interest.

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Published

2025-04-28