Age structure of tuberculosis incidence among the female population of Ukraine in 2019-2023
DOI:
https://doi.org/10.15574/HW.2025.6(186).59Keywords:
tuberculosis, female population, morbidity, age structure, epidemiology, monitoring, UkraineAbstract
Tuberculosis remains a leading infectious disease and a significant medical and social problem for the public health system of Ukraine. It is important to monitor the morbidity among women, because the age structure reflects the epidemic process, socio-economic factors and the effectiveness of anti-tuberculosis measures.
Aim - to analyze the dynamics and age structure of tuberculosis incidence among the female population of Ukraine in 2019-2023.
Materials and methods. A retrospective descriptive epidemiological study was conducted based on official statistical data of the Public Health Center of the Ministry of Health of Ukraine regarding the number of registered cases of tuberculosis among women in Ukraine in 2019-2023. The absolute indicators and their share in the overall structure of morbidity were analyzed. A comparative analysis of the dynamics by years and age groups was carried out with the determination of trends and structural changes. Methods of descriptive statistics, structural and comparative analysis were used.
The results. During 2019-2023, 27,833 cases of tuberculosis among the female population were registered in Ukraine. A decrease in the total number of cases was established from 7,529 in 2019 to 4,744 in 2022 (-36.9%), with a further increase to 5,057 in 2023. The incidence structure was dominated by women aged 35-44 (26.3% of the total number of cases). The age groups 45-54 years and 25-34 years also accounted for a significant share. A trend towards an increase in the specific weight of women aged 65 and older was revealed - from 11.8% in 2019 to 16.7% in 2023.The share of children and adolescents (0-17 years old) remained relatively low (about 6%), but in 2023 there was a certain increase in indicators in the age groups 5-14 years old.
Conclusions. In 2019-2023, Ukraine observed a general decrease in the registered incidence of tuberculosis among women with a minimum level in 2022 and a partial recovery in 2023. A shift in the age structure towards older age groups has been established. The decrease in indicators in 2020-2022 requires careful interpretation, taking into account the impact of the COVID-19 pandemic and military events on the completeness of detection and registration of cases.
The authors declare no conflict of interest.
References
Cao W, Fu X, Li H, Bei J, Li L, Wang L. (2024, Jun 6). Tuberculosis in pregnancy and assisted reproductive technology. Drug Discov Ther. 18(2): 80-88. https://doi.org/10.5582/ddt.2024.01007; PMid:38631867
Chiang SS, Murray MB, Kay AW, Dodd PJ. (2025, Mar 5). Factors driving adolescent tuberculosis incidence by age and sex in 30 high-tuberculosis burden countries: a mathematical modelling study. BMJ Glob Health. 10(3): e015368. https://doi.org/10.1136/bmjgh-2024-015368; PMid:40044460 PMCid:PMC11883532
Dabitao D, Bishai WR. (2023). Sex and Gender Differences in Tuberculosis Pathogenesis and Treatment Outcomes. Curr Top Microbiol Immunol. 441: 139-183. https://doi.org/10.1007/978-3-031-35139-6_6; PMid:37695428
Gupta M, Srikrishna G, Klein SL, Bishai WR. (2022, Aug). Genetic and hormonal mechanisms underlying sex-specific immune responses in tuberculosis. Trends Immunol. 43(8): 640-656. https://doi.org/10.1016/j.it.2022.06.004; PMid:35842266 PMCid:PMC9344469
Harikumar Parvathy G, Hertz D, Bhandiwad D, Eggers L, von Borstel L, Behrends J et al. (2025, Nov 14). Sex Differences in Vaccine-Induced Immunity and Protection Against Mycobacterium tuberculosis. J Infect Dis. 232(5): 1187-1197. https://doi.org/10.1093/infdis/jiaf277; PMid:40569757
Ramos Robles B, Valdez RA, Hernández Almaraz M, Castañeda Mayorga SR, Mata Espinosa D, Barrios Payan J et al. (2023, Jan). Immunoendocrine abnormalities in the female reproductive system, and lung steroidogenesis during experimental pulmonary tuberculosis. Tuberculosis (Edinb). 138: 102274. https://doi.org/10.1016/j.tube.2022.102274; PMid:36463716
Min J, Park JS, Kim HW, Ko Y, Oh JY, Jeong YJ et al. (2023, Apr 13). Differential effects of sex on tuberculosis location and severity across the lifespan. Sci Rep. 13(1): 6023. https://doi.org/10.1038/s41598-023-33245-5; PMid:37055508 PMCid:PMC10102118
Neudecker D, Altpeter E, Ritz N, Fritschi N. (2025, May 29). Sex distribution in tuberculosis disease in children, adolescents, and adults in a low-incidence country: a retrospective population-based cohort study. Swiss Med Wkly. 155: 4187. https://doi.org/10.57187/s.4187; PMid:40931799
Yang H, Ruan X, Li W, Xiong J, Zheng Y. (2024, Nov 11). Global, regional, and national burden of tuberculosis and attributable risk factors for 204 countries and territories, 1990-2021: a systematic analysis for the Global Burden of Diseases 2021 study. BMC Public Health. 24(1): 3111. https://doi.org/10.1186/s12889-024-20664-w; PMid:39529028 PMCid:PMC11552311
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