Analysis of sexual function in women with an implanted mid-urethral sling
DOI:
https://doi.org/10.15574/HW.2025.6(186).1017Keywords:
sexual function, stress urinary incontinence, sling, pelvic surgery, laser therapy, estrogensAbstract
Stress urinary incontinence negatively affects quality of life, social activity, and sexual health in women. In this context, the improvement of sexual function is a crucial indicator of treatment efficacy for urinary incontinence in this patient population.
Aim - to analyze sexual function as a key component of the clinical effectiveness of sling surgery in women with stress urinary incontinence.
Materials and methods. A comparative study of sexual function after sling surgical procedures for the correction of stress urinary incontinence was conducted in women under 50 years of age in two representative subgroups: IA (n=28) underwent free synthetic sling placement (TVT), and IB (n=30) underwent TVT-O combined with postoperative vaginal laser therapy. Women aged 50 and older were also divided into two subgroups: IIA (n=14) underwent TVT; IIB (n=10) underwent TVT-O followed by a postoperative course of promestriene (natural and semi-synthetic estrogens). Statistical analysis was performed using the SPSS 21 software package.
Results. Vaginal laser therapy after TVT-O sling implantation significantly improved sexual function in a greater number of patients under 50 years of age compared to the corresponding comparison group. Vaginal promestriene therapy after TVT-O did not significantly affect the quality of sexual life in women aged 50 and older.
Conclusions. Sexual function is an important component in evaluating the effectiveness of sling surgical intervention in women with stress urinary incontinence. Differentiated assessment of clinical manifestations of sexual dysfunction using specialized questionnaires allows identification of potential directions for their correction during further treatment.
The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of participating institution. Informed consent was obtained from all patients.
The authors declare no conflict of interest.
References
Aguiar LB, Politano CA, Costa-Paiva L, Juliato CRT. (2020). Efficacy of Fractional CO2 Laser, Promestriene, and Vaginal Lubricant in the Treatment of Urinary Symptoms in Postmenopausal Women: A Randomized Clinical Trial. Lasers Surg Med. 52(8): 713-720. https://doi.org/10.1002/lsm.23220; PMid:31990089
Bohadelnikova KI, Chaika KV, Yatsyna OI, Bondaruk VP, Fedko YeV, Bodnarchuk OV. (2024). Efficacy and safety of postoperative vaginal laser therapy in women with an implanted TVT-O sling for the treatment of stress urinary incontinence. Ukrainian Journal of Perinatology and Pediatrics. 4(100): 63-69. https://doi.org/10.15574/PP.2024.4(100).6369
Bohadelnikova KI, Chaika KV, Yatsyna OI, Rud VO, Shamrai VA. (2025). Study of possibilities to improve the effectiveness of stress urinary incontinence treatment in menopausal women with an implanted TVT-O sling. Ukrainian Journal of Perinatology and Pediatrics. 1(101): 67-73. https://doi.org/10.15574/PP.2025.1(101).6773
Chaika КV, Lavrenuik YV. (2018). Sexual function analysis as one of the most important component of life quality in patients with early manifested genital prolapse. Zbirnyk naukovykh prats spivrobitnykiv NMAPO imeni P.L. Shupyka. 32: 103-113.
Ford AA, Rogerson L, Cody JD, Aluko P, Ogah JA. (2017). Mid-urethral sling operations for stress urinary incontinence in women. Cochrane Database Syst Rev. 7(7): CD006375. https://doi.org/10.1002/14651858.CD006375.pub4; PMid:28756647 PMCid:PMC6483329
Gallo K, Weiner H, Mishra K. (2024). An update on surgical management for stress urinary incontinence. Curr Opin Obstet Gynecol. 36(6): 433-438. https://doi.org/10.1097/GCO.0000000000000989; PMid:39361324
Gray T, Li W, Campbell P, Jha S, Radley S. (2023). Evaluation of coital incontinence by electronic questionnaire: prevalence, associations and outcomes in women attending a urogynaecology clinic. Int Urogynecol J. 29(7): 969-978. https://doi.org/10.1007/s00192-017-3380-x; PMid:28620792
Harland N, Walz S, Eberli D, Schmid FA, Aicher WK, Stenzl A et al. (2023). Stress Urinary Incontinence: An Unsolved Clinical Challenge. Biomedicines. 11(9): 2486. https://doi.org/10.3390/biomedicines11092486; PMid:37760927 PMCid:PMC10525672
Hogewoning CR, Gietelink L, Pelger RC, Hogewoning CJ, Bekker MD, Elzevier HW. (2015). The introduction of mid-urethral slings: an evaluation of literature. Int Urogynecol J. 26(2): 229-234. https://doi.org/10.1007/s00192-014-2488-5; PMid:25143007
Imamura M, Hudson J, Wallace SA, MacLennan G, Shimonovich M, Omar MI, (2019). Surgical interventions for women with stress urinary incontinence: systematic review and network meta-analysis of randomised controlled trials. BMJ. 365: l1842. https://doi.org/10.1136/bmj.l1842; PMid:31167796 PMCid:PMC6549286
Lauterbach R, Aharoni S, Justman N, Farago N, Gruenwald I, Lowenstein L. (2022). The efficacy and safety of a single maintenance laser treatment for stress urinary incontinence: a double-blinded randomized controlled trial. Int Urogynecol J. 33(12): 3499-3504. https://doi.org/10.1007/s00192-022-05103-x; PMid:35195738 PMCid:PMC8864590
Mackova K, Van Daele L, Page AS, Geraerts I, Krofta L, Deprest J. (2020). Laser therapy for urinary incontinence and pelvic organ prolapse: a systematic review. BJOG. 127(11): 1338-1346. https://doi.org/10.1111/1471-0528.16273; PMid:32333820
Nambiar AK, Arlandis S, Bø K, Cobussen-Boekhorst H, Costantini E, de Heide M et al. (2022). European Association of Urology Guidelines on the Diagnosis and Management of Female Non-neurogenic Lower Urinary Tract Symptoms. Part 1: Diagnostics, Overactive Bladder, Stress Urinary Incontinence, and Mixed Urinary Incontinence. Eur Urol. 82(1): 49-59. https://doi.org/10.1016/j.eururo.2022.01.045; PMid:35216856
Offiah I, Freeman R; MONARC™ study group. (2021). Long-term efficacy and complications of a multicentre randomised controlled trial comparing retropubic and transobturator mid-urethral slings: a prospective observational study. BJOG. 128(13): 2191-2199. https://doi.org/10.1111/1471-0528.16899; PMid:34478604
Patel UJ, Godecker AL, Giles DL, Brown HW. (2022). Updated Prevalence of Urinary Incontinence in Women: 2015-2018 National Population-Based Survey Data. Female Pelvic Med Reconstr Surg. 28(4): 181-187. https://doi.org/10.1097/SPV.0000000000001127; PMid:35030139
Pinheiro Sobreira Bezerra LR, Britto DF, Ribeiro Frota IP, Lira do Nascimento S, Morais Brilhante AV et al. (2020). The Impact of Urinary Incontinence on Sexual Function: A Systematic Review. Sex Med Rev. 8(3): 393-402. https://doi.org/10.1016/j.sxmr.2019.06.009; PMid:32409182
Rogers RG, Kammerer-Doak D, Darrow A, Murray K, Olsen A et al. (2004). Sexual function after surgery for stress urinary incontinence and/or pelvic organ prolapse: a multicenter prospective study. Am J Obstet Gynecol. 191(1): 206-210. https://doi.org/10.1016/j.ajog.2004.03.087; PMid:15295367
Romashchenko O, Hryhorenko V, Melnykov S, Biloholovska V, Myronenko N, Dzhuraieva L. (2022). Sexual dysfunctions in women of different ages. Choloviche zdorovia, henderna ta psykhosomatychna medytsyna. 1-2(14-15): 68-74.
Seki AS, Bianchi-Ferraro AMHM, Fonseca ESM, Sartori MGF, Girão MJBC, Jarmy-Di Bella ZIK. (2022). CO2 Laser and radiofrequency compared to a sham control group in treatment of stress urinary incontinence (LARF study arm 3). A randomized controlled trial. Int Urogynecol J. 33(12): 3535-3542. https://doi.org/10.1007/s00192-022-05091-y; PMid:35254473
Todhunter-Brown A, Hazelton C, Campbell P, Elders A, Hagen S, McClurg D. (2022). Conservative interventions for treating urinary incontinence in women: an Overview of Cochrane systematic reviews. Cochrane Database Syst Rev. 9(9): CD012337. https://doi.org/10.1002/14651858.CD012337.pub2; PMid:36053030 PMCid:PMC9437962
Wang L, Ye L. (2024). Clinical Efficacy and Safety Meta-Analysis of Different Surgical Approaches for Female Stress Urinary Incontinence. Arch Esp Urol. 77(5): 479-490. https://doi.org/10.56434/j.arch.esp.urol.20247705.67; PMid:38982776
Weisberg E, Ayton R, Darling G, Farrell E, Murkies A, O'Neill S et al. (2005). Endometrial and vaginal effects of low-dose estradiol delivered by vaginal ring or vaginal tablet. Climacteric. 8(1): 83-92. https://doi.org/10.1080/13697130500087016; PMid:15804736
Zhang C, Tong J, Zhu L, Zhang L, Xu T et al. (2017). A Population-Based Epidemiologic Study of Female Sexual Dysfunction Risk in Mainland China: Prevalence and Predictors. J Sex Med. 14(11): 1348-1356. https://doi.org/10.1016/j.jsxm.2017.08.012; PMid:29110805
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